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Television actress, singer, movie star, designer and philanthropist, Alyssa Jayne Milano was born in New York City to a fashion designer and talent manager mother and a film music editor father. She began her career aged eight when she won a part starring in the Broadway show Annie.

Aged eleven, she played a role in the TV show Who’s the Boss? The family then relocated to Hollywood. When she was in her teens, she came out with a teenage workout video called Teen Steam.

Milano is best remembered for her roles on TV such as Who’s the Boss, Charmed and her return to NBC’s hit comedy serial My Name is Earl in 2007. She gained immense popularity as a television actress. The audience loved her as Jennifer Mancini on Melrose Place (1997–1998), Meg Winston in Spin City and Phoebe Halliwell in Charmed (1998–2006). Charmed aired for nine years and had a global audience in Europe, Africa, Asia and Australia.

She attempted to break out of her “nice girl” image with roles in films like Casualties of Love: The Long Island Lolita Story (1992), Embrace of the Vampire (1994), Confessions of a Sorority Girl (1994), Deadly Sins (1995), and Poison Ivy II: Lily (1995). Some of Milano’s other films include Hugo Pool (1997), with Sean Penn and Robert Downey Jr, and Fear (1996). Recently, she lent her voice for Disney’s sequel to the animated favorite Lady and the Tramp.

Alyssa Milano is a UNICEF Goodwill Ambassador for the US. She has travelled with UNICEF field officers to India and Angola. In 2002, Milano, who loves photography, raised nearly US$50,000 through a photography exhibition in Los Angeles for South African women and children suffering from AIDS. In the fall of 2004, she launched UNICEF’s Trick or Treat campaign as an official spokesperson. She is a strong supporter of PETA and is also the founding ambassador for the Global Network for Neglected Tropical Disease Control (GNNTDC) which fights to control neglected tropical diseases (NTDs) in the world’s poorest countries.

An avid baseball fan, she has also launched her own sports clothing line called Touch. She has teamed up with the NFL, the NBA and the NHL to make Touch available to fans of football, basketball and hockey.